Scientific Link to Autism Identified

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Vaccines Cause Autism, News From Scientific Think Tank States:

MMR isnot the only vaccine containing this gelatin. Here are the vaccines that co ntain this gelatin and the amount in each:

DTaP 0.0015 mg

Influenza 0.025 mg

Measles 14.5 mg

Mumps 14.5mg

Rubella 14.5 mg

MMR II 14.5 mg

Varicella 12.5 mg

Shingles 15.58 mg

Rabies < 12 mg

http://www.laleva.org/eng/2009/11/vaccines_cause_autism_news_from_scientific_think_tank_states.html

Homeostasis or homoeostasis is the property of an open system, especially living organisms, to regulate its internal environment so as to maintain a stable condition, by means of multiple dynamic equilibrium adjustments controlled by interrelated regulation mechanisms.

http://www.bio-medicine.org/Biology-Definition/Homeostasis/

Vaccines and Immune Suppression:

http://vran.org/about-vaccines/general-issues/doctors-speak/vaccines-and-immune-suppression/

Just, M. A., et al. Cortical activation and synchronization during sentence comprehension in high-functioning autism: evidence of underconnectivity. Brain. 127(Part 8):1811-1221, 2004.

Carnegie Mellon University, Center for Cognitive Brain Imaging, Department of Psychology, Pittsburgh, PA, USA.

The brain activation of a group of high-functioning autistic participants was measured using functional MRI during sentence comprehension and the results compared with those of a Verbal IQ-matched control group. The groups differed in the distribution of activation in two of the key language areas. The autism group produced reliably more activation than the control group in Wernicke's (left laterosuperior temporal) area and reliably less activation than the control group in Broca's (left inferior frontal gyrus) area. Furthermore, the functional connectivity, i.e. the degree of synchronization or correlation of the time series of the activation, between the various participating cortical areas was consistently lower for the autistic than the control participants. These findings suggest that the neural basis of disordered language in autism entails a lower degree of information integration and synchronization across the large-scale cortical network for language processing. The article presents a theoretical account of the findings, related to neurobiological foundations of underconnectivity in autism.

In-Tele-Health

Blaxill, M. F., et al. Thimerosal and autism? A plausible hypothesis that should not be dismissed. Med Hypotheses. 62(5):788-794, 2004.

Safe Minds (Sensible Action For Ending Mercury-Induced Neurological Disorders), New Jersey, USA.

The autism-mercury hypothesis first described by Bernard et al. has generated much interest and controversy. The Institute of Medicine (IOM) reviewed the connection between mercury-containing vaccines and neurodevelopmental disorders, including autism. They concluded that the hypothesis was biologically plausible but that there was insufficient evidence to accept or reject a causal connection and recommended a comprehensive research program. Without citing new experimental evidence, a number of observers have offered opinions on the subject, some of which reject the IOM's conclusions. In a recent review, Nelson and Bauman argue that a link between the preservative thimerosal, the source of the mercury in childhood vaccines, is improbable. In their defense of thimerosal, these authors take a narrow view of the original hypothesis, provide no new evidence, and rely on selective citations and flawed reasoning. The authors provide evidence here to refute the Nelson and Bauman critique and to defend the autism-mercury hypothesis.

· Geier, D. A., et al. An assessment of the impact of thimerosal on childhood neurodevelopmental disorders. Pediatr Rehabil. 6(2):97-102, 2003.

The Genetic Centers of America, Silver Spring, MD, USA.

The prevalence of autism in the US has risen from 1 in approximately 2500 in the mid-1980s to 1 in approximately 300 children in the mid-1990s. The purpose of this study was to evaluate whether mercury from thimerosal in childhood vaccines contributed to neurodevelopmental disorders. Neurodevelopmental disorder dose-response curves for increasing mercury doses of thimerosal in childhood vaccines were determined based upon examination of the Vaccine Adverse Events Reporting System (VAERS) database and the 2001 US' Department of Education Report. The instantaneous dosage of mercury children received in comparison to the Food and Drug Administration (FDA)'s maximum permissible dose for the oral ingestion of methylmercury was also determined. The dose-response curves showed increases in odds ratios of neurodevelopmental disorders from both the VAERS and US Department of Education data closely linearly correlated with increasing doses of mercury from thimerosal-containing childhood vaccines and that for overall odds ratios statistical significance was achieved. Similar slopes and linear regression coefficients for autism odds ratios in VAERS and the US Department of Education data help to mutually validate each other. Controls employed in the VAERS and US Department of Education data showed minimal biases. The evidence presented here shows that the occurrence of neurodevelopmental disorders following thimerosal-containing childhood vaccines does not appear to be coincidental.

· Geier, M. R., et al. Neurodevelopmental disorders after thimerosal-containing vaccines: a brief communication. Exp Biol Med (Maywood). 228(6):660-664, 2003.

The Genetic Centers of America, Silver Spring, Maryland, USA

The authors were initially highly skeptical that differences in the concentrations of thimerosal in vaccines would have any effect on the incidence rate of neurodevelopmental disorders after childhood immunization. This study presents the first epidemiologic evidence, based upon tens of millions of doses of vaccine administered in the United States, that associates increasing thimerosal from vaccines with neurodevelopmental disorders. Specifically, an analysis of the Vaccine Adverse Events Reporting System (VAERS) database showed statistical increases in the incidence rate of autism (relative risk [RR] = 6.0), mental retardation (RR = 6.1), and speech disorders (RR = 2.2) after thimerosal-containing diphtheria, tetanus, and acellular pertussis (DTaP) vaccines in comparison with thimerosal-free DTaP vaccines. The male/female ratio indicated that autism (17) and speech disorders (2.3) were reported more in males than females after thimerosal-containing DTaP vaccines, whereas mental retardation (1.2) was more evenly reported among male and female vaccine recipients. Controls were employed to determine if biases were present in the data, but none were found. It was determined that overall adverse reactions were reported in similar-aged populations after thimerosal-containing DTaP (2.4 +/- 3.2 years old) and thimerosal-free DTaP (2.1 +/- 2.8 years old) vaccinations. Acute control adverse reactions such as deaths (RR = 1.0), vasculitis (RR = 1.2), seizures (RR = 1.6), ED visits (RR = 1.4), total adverse reactions (RR = 1.4), and gastroenteritis (RR = 1.1) were reported similarly after thimerosal-containing and thimerosal-free DTaP vaccines. An association between neurodevelopmental disorders and thimerosal-
containing DTaP vaccines was found, but additional studies should be conducted to confirm and extend this study.

· Geier, D. A., et al. A comparative evaluation of the effects of MMR immunization and mercury doses from thimerosal-
containing childhood vaccines on the population prevalence of autism. Med Sci Monit. 10(3):PI33-39, 2004.

President, MedCon, Inc, Silver Spring, MD, USA.

The purpose of the study was to evaluate the effects of MMR immunization and mercury from thimerosal-
containing childhood vaccines on the prevalence of autism. Evaluations of the Biological Surveillance Summaries of the Centers for Disease Control and Prevention (CDC), the U.S. Department of Education datasets, and the CDC's yearly live birth estimates were undertaken It was determined that there was a close correlation between mercury doses from thimerosal--containing childhood vaccines and the prevalence of autism from the late 1980s through the mid-1990s. In contrast, there was a potential correlation between the number of primary pediatric measles-containing vaccines administered and the prevalence of autism during the 1980s. In addition, it was found that there were statistically significant odds ratios for the development of autism following increasing doses of mercury from thimerosal-containing vaccines (birth cohorts: 1985 and 1990-1995) in comparison to a baseline measurement (birth cohort: 1984). The contribution of thimerosal from childhood vaccines (>50% effect) was greater than MMR vaccine on the prevalence of autism observed in this study. The results of this study agree with a number of previously published studies. These studies have shown that there is biological plausibility and epidemiological evidence showing a direct relationship between increasing doses of mercury from thimerosal-containing vaccines and neurodevelopmental disorders, and measles-containing vaccines and serious neurological disorders. It is recommended that thimerosal be removed from all vaccines, and additional research be undertaken to produce a MMR vaccine with an improved safety profile.

In-Tele-Health

Piyasirisilp, S., et al. Neurological adverse events associated with vaccination. Curr Opin Neurol. 15(3):333-338, 2002.

Division of Neurology, Department of Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Several reporting systems have been established to monitor adverse events following immunization. The present review summarizes data on neurologic complications following vaccination, and provides evidence that indicates whether they were directly associated with the vaccines. These complications include autism caused by measles vaccine.

In-Tele-Health

Gelatin, used in vaccines, is also related to the transmission of Mad Cow Disease...Alzheimer's....We also find that gelatin is included in most pharmaceuticals for stabilization.

Expression and characterization of a low molecular weight recombinant human gelatin: development of a substitute for animal-derived gelatin with superior features.

Removal of gelatin from live vaccines and DTaP-an ultimate solution for vaccine-related gelatin allergy:

From the early 1990s infants started to receive acellular pertussis vaccine combined with diphtheria and tetanus toxoids (DTaP) before live vaccines such as measles, rubella, and mumps vaccines, which contained gelatin as a stabilizer. Then, an increasing number of cases of anaphylactic/allergic reactions to those live vaccines were reported. Almost all these cases had a previous history of receiving three or four doses of DTaP containing gelatin.

http://www.ncbi.nlm.nih.gov/pubmed/14624794?dopt=Abstract

Work by Reporter Brian Deer is at Center of Investigation Being Conducted by Medical Regulators

(Austin, Texas) – The Press Complaints Commission (PCC) of London, an independent body that oversees journalism fairness in the UK, has issued an interim order calling for the Sunday Times to remove stories written by Brian Deer about Dr. Andrew Wakefield from its web site. Dr. Wakefield had filed an extensive complaint with the PCC regarding errors of fact in Deer’s reportage on the MMR vaccine and its possible relationship to autism. The General Medical Council (GMC) in the UK is presently hearing evidence involving Dr. Wakefield and two of his colleagues following a complaint to the GMC by Deer himself. The PCC decision today appears to indicate there are questions about the accuracy of the Deer stories.

The PCC complaint by Dr. Wakefield provides clear evidence that Deer’s allegations of “data fixing” by him are false. The complaint also accused Deer of an undisclosed conflict of interest since Deer also failed to disclose in his articles that he was the person who made the original complaint to the GMC, misleading the newspaper’s readers over the accuracy of his reporting.

“Given the ongoing nature of the dispute,” Stephen Abell of the PCC wrote, “the articles should be removed from the newspaper’s website until this matter has been concluded. This would not be an admission of any liability on the part of the newspaper.”

Although media are expected to respond promptly to complaints through an informal process, the Sunday Times took more than three months to answer detailed issues raised by Dr. Wakefield, and called upon legal representation to write the paper’s response. Despite this they have failed to produce any evidence of “data fixing” by Dr. Wakefield. In its letter to Dr. Wakefield, the PCC “expressed concern at the initial slowness of the newspaper’s response.” The PCC said it delayed a complete ruling until it has a fuller accounting of all information submitted to the GMC, but that the outcome of the GMC hearing is not relevant to a final decision by the PCC.

“My contention has always been,” Dr. Wakefield explained, “And it always will be that journalism, before it is published, must stand on its merits with good documentation, sources, and corroboration. Deer’s stories fail on every count. I see no connection between the GMC’s hearing and a decision by the PCC. If the Sunday Times cannot defend the information today, which it can’t, then it was unable to do so at the time of publication.”

Wakefield has been one of the subjects of the longest GMC hearing in history. Although the hearing was expected to be concluded in August 2009, information from attorneys involved in presenting evidence indicate the case is not likely to be decided upon by the panel until December and may not conclude until early 2010.

About Thoughtful House: Thoughtful House advocates a multi-disciplinary treatment approach to treating autism and supports a 'safety-first' vaccination policy. The research program at Thoughtful House is dedicated to understanding the biological origins of childhood developmental disorders and establishing best practices in treating children affected by these disorders.

Read Complaint: Submission to the UK Press Complaints Commission
Read Complaint Addendum: Submission addendum to the UK Press Complaints Commission

http://thoughtfulhouse.org/pr/sunday-times-ordered-to-remove-brian-deer-MMR-stories.php